Cruz Bay, located on the west coast of Saint John, is the island's largest commercial center and the location of the main port on Saint John. The primary access to Saint John is through Cruz Bay Harbor. Frequent barge and ferry, including car ferry, service connects Saint John to the neighboring more-developed island of Saint Thomas. Ferries also run regularly between Cruz Bay and Tortola, Virgin Gorda, and Jost Van Dyke in the British Virgin Islands.

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